Best ERP (Enterprise Resource Planning) Systems

SAP S/4HANA
SAP’s flagship ERP, optimized for its in-memory HANA database. It is built for large organizations needing comprehensive coverage: finance, procurement, manufacturing, supply chain, and cross-industry support. It supports cloud, on-premise, or hybrid deployment. 
Wikipedia
+1

Oracle ERP Cloud (Oracle Fusion / Oracle Cloud ERP)
Oracle’s cloud ERP suite covers financials, procurement, project management, supply chain, and more. It’s often used by large enterprises that want cloud scalability plus depth in enterprise modules. 
Wikipedia

NetSuite ERP
A popular cloud ERP, especially among mid-size firms, offering unified modules for accounting, inventory, order management, CRM, and analytics. It is praised for flexibility and scalability. 
Top 10 ERP
+1

Microsoft Dynamics 365
A modular, flexible ERP + CRM solution that works well for companies already in the Microsoft stack (Office, Azure). You can adopt only the modules you need (finance, operations, sales, etc.). 
Zapier
+1

Infor / Infor CloudSuite
Infor designs industry-specific ERP suites (for manufacturing, distribution, healthcare, etc.). Their CloudSuite offerings embed domain knowledge so you get more out-of-the-box fit for certain verticals. 
CRM.org
+1

Epicor
Often selected by manufacturing or industrial firms. Epicor is known for strong production, shop floor, and supply chain features tailored to discrete manufacturing. 
Productive
+1

Acumatica
A cloud ERP geared toward small to mid-sized businesses. It emphasizes usability and flexibility, with modern architecture and scalability. 
Zapier
+1

Sage (e.g. Sage X3 / Sage Intacct / other Sage ERP offerings)
Sage targets the mid-market, focusing on robust financials and distribution management without the complexity of the largest enterprise systems. 
Top 10 ERP
+1

SAP Business One / SAP Business ByDesign
These are SAP’s ERP offerings for smaller and mid-sized companies:

Business One is for small to medium enterprises (SMEs), with core functions (finance, sales, operations). 
Wikipedia

ByDesign is SAP’s cloud ERP aimed at mid-market firms (though its ongoing roadmap has been debated).

Open / Open-Source ERP Options (Compiere, etc.)
For businesses wanting more control or lower licensing costs, open or hybrid systems exist. Compiere is one example of an open-source ERP / CRM framework that supports distribution, manufacturing, etc. 
Wikipedia

Plex (by Rockwell)
Plex is a cloud-native ERP engineered specifically for manufacturing. It combines traditional ERP capabilities (finance, order management, inventory, procurement) with deep shop-floor / MES / manufacturing execution functionality, quality, and supply chain visibility in one platform.

Odoo

Odoo is an open-source ERP platform that offers a modular suite of integrated business applications (e.g. CRM, accounting, inventory, manufacturing) to centralize and streamline a company’s operations.